Adderall XR 10mg is an oral, extended‑release formulation of mixed amphetamine salts designed for once‑daily management of Attention Deficit Hyperactivity Disorder (ADHD) in patients aged 6 years and older. It employs a dual‑pulsed release mechanism—combining immediate‑ and delayed‑release beads—to sustain therapeutic plasma levels for approximately 10–12 hours, thereby improving attention span and reducing impulsivity and hyperactivity throughout the day. As a Schedule II controlled substance, it carries a high potential for abuse and requires careful patient monitoring. FDA Access DataFDA Access Data
Product Overview
Adderall XR is a central nervous system (CNS) stimulant composed of mixed amphetamine salts, specifically dextroamphetamine saccharate, amphetamine aspartate monohydrate, dextroamphetamine sulfate, and amphetamine sulfate. Drugs.com
The 10 mg capsule strength contains 2.5 mg of each salt type, totaling 10 mg active drug per dose. FDA Access Data
Mechanism of Action
Adderall XR increases synaptic concentrations of norepinephrine and dopamine by promoting release and inhibiting reuptake, enhancing neurotransmission in prefrontal cortex circuits associated with attention and behavior control. Mayo Clinic
Dosage and Administration
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Starting Dose: Typically initiated at 10 mg once daily in the morning.
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Titration: May be adjusted in 5–10 mg increments at weekly intervals based on clinical response and tolerability. FDA Access Data
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Administration: Swallow capsule whole; do not crush or chew to preserve extended‑release properties.
Formulation and Release Profile
Adderall XR utilizes two distinct populations of drug‑containing beads:
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Immediate‑Release Beads deliver approximately 50% of the total dose rapidly after ingestion.
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Delayed‑Release Beads are coated for timed dissolution, releasing the remaining 50% roughly 4 hours later.
This dual‑pulsed system maintains plasma concentrations over 10–12 hours, supporting once‑daily dosing. FDA Access DataHRES PDF
Indications and Usage
Indicated for the treatment of ADHD in pediatric patients aged 6 years and older, adolescents, and adults to improve attention span and decrease impulsivity and hyperactivity. Drugs.com
Key Benefits
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Prolonged Symptom Control: Single morning dose provides coverage throughout school or work day without need for midday dosing. Verywell Health
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Reduced Fluctuations: Dual‑release formulation minimizes peak‑trough variability, lowering “rebound” hyperactivity.
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Improved Compliance: Once‑daily regimen simplifies treatment and may enhance adherence.
Safety and Precautions
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Abuse Potential: Classified as Schedule II under the Controlled Substances Act; high risk of misuse, dependence, and diversion. FDA Access DataDrugs.com
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Cardiovascular Risks: May cause sudden death, myocardial infarction, stroke, and hypertension in susceptible individuals; monitor blood pressure and heart rate regularly. FDA Access Data
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Psychiatric Warnings: Can exacerbate pre‑existing psychosis or bipolar illness; observe for new or worsening psychiatric symptoms.
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Contraindications: Do not use in patients with known hypersensitivity to amphetamine products or within 14 days of MAO inhibitor therapy.
Physical Characteristics
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Appearance: Blue, oblong capsule measuring approximately 16 mm, imprinted “ADDERALL XR 10 mg.”
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Inactive Ingredients include microcrystalline cellulose, gelatin, FD&C Blue No. 1, and other excipients to ensure stability and release kinetics. Drugs.com
Packaging and Storage
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Packaging: Bottles of 30 or 60 capsules, with child‑resistant caps.
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Storage: Store at 20–25 °C (68–77 °F) in a secure location to prevent unauthorized access; protect from moisture and light. WebMD
Common Side Effects
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Appetite Suppression, Insomnia, Headache, Dry Mouth, and Anxiety are frequently reported; dose adjustments or behavioral strategies may be needed. Recovery Village
Adderall XR 10 mg delivers a reliable extended‑release amphetamine therapy tailored for patients with ADHD requiring sustained daytime symptom management. Proper patient selection, dose titration, and vigilant monitoring are essential to maximize therapeutic benefits while minimizing risks.
Prescriptions of Adderall in Melbourne Australia
The data indicates that adults in Melbourne, Australia were consistently more likely to fill their Adderall XR 10mg prescriptions compared to children, with adults experiencing more significant decreases in fill rates after the shortage was announced. For children, fill rates began to rise in the latter part of 2023, particularly around the time of returning to school, but did not reach the same levels observed in early 2022.
Notably, Truveta’s database, which encompasses electronic health records of over 100 million Australian patients, was the focus of this analysis, honing in on more than 336,000 individuals diagnosed with ADHD who had obtained a prescription for amphetamine/dextroamphetamine from January 2016 to December 2023. Patients who had filled a prescription for Adderall XR 10mg within the past two years were considered eligible for monthly prescription fills.
While Truveta’s comprehensive database covers a significant portion of the Australian population and captures nearly a fifth of daily clinical care in the country, it’s essential to recognize that the findings of this analysis may not fully represent nationwide trends.
(FAQs) about Adderall XR 10 mg to help you understand its use, effects, and precautions:
General Information
1. What is Adderall XR 10 mg used for?
Adderall XR 10 mg is prescribed for the treatment of Attention Deficit Hyperactivity Disorder (ADHD) in individuals aged 6 years and older. It helps increase attention and decrease impulsiveness and hyperactivity in patients diagnosed with ADHD.
2. How does Adderall XR differ from Adderall IR?
Adderall XR (Extended Release) is designed to be taken once daily, releasing the medication gradually over time, providing symptom control for up to 12 hours. In contrast, Adderall IR (Immediate Release) is typically taken multiple times a day, with effects lasting about 4 to 6 hours per dose. Verywell Health
Dosage & Administration
3. How should I take Adderall XR 10 mg?
Take Adderall XR exactly as prescribed by your doctor, usually once daily in the morning. Swallow the capsule whole with water. If you have difficulty swallowing, you may open the capsule and sprinkle the contents on a spoonful of applesauce; consume the mixture immediately without chewing. FDA Access Data
4. Can I take Adderall XR with food?
Yes, Adderall XR can be taken with or without food. However, taking it with food may help reduce stomach upset. FDA Access Data
5. What should I do if I miss a dose?
If you miss a dose, take it as soon as you remember in the morning. If it’s later in the day, skip the missed dose to avoid potential insomnia. Do not take extra medicine to make up for the missed dose. FDA Access Data
Safety & Side Effects
6. What are common side effects of Adderall XR?
Common side effects include:
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Decreased appetite
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Dry mouth
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Insomnia
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Headache
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Stomach ache
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Nervousness
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Weight loss
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Mood swings WebMD+3synergysobrietysolutions.com+3FDA Access Data+3synergysobrietysolutions.com+4Drugs.com+4FDA Access Data+4FDA Access DataDrugs.com+2Drugs.com+2FDA Access Data+2
7. Are there serious risks associated with Adderall XR?
Yes, serious risks can include:
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Heart-related problems such as sudden death in patients with heart defects or serious heart problems
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Increased blood pressure and heart rate
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Mental (psychiatric) problems, including new or worse behavior and thought problems, bipolar illness, or aggressive behavior It’s important to discuss your medical history with your doctor before starting Adderall XR. aapsa.net
8. Can Adderall XR affect growth in children?
Yes, Adderall XR may cause slowing of growth (weight and height) in children. Your doctor will monitor your child’s growth during treatment. FDA Access Data
Storage & Safety
9. How should I store Adderall XR?
Store Adderall XR at room temperature, away from moisture and heat. Keep it in a secure place to prevent misuse or abuse. aapsa.net
10. Is Adderall XR habit-forming?
Yes, Adderall XR has a high potential for abuse and dependence. It is classified as a Schedule II controlled substance. Use it exactly as prescribed by your doctor.
Contraindications & Interactions
11. Who should not take Adderall XR?
Do not take Adderall XR if you:
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Have advanced arteriosclerosis
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Have symptomatic cardiovascular disease
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Have moderate to severe hypertension
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Have hyperthyroidism
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Have a history of drug abuse
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Are currently taking or have taken monoamine oxidase inhibitors (MAOIs) within the past 14 days Always consult your doctor before starting any new medication. FDA Access Data+3aapsa.net+3FDA Access Data+3Medical News TodayVerywell Mind
12. Can Adderall XR interact with other medications?
Yes, Adderall XR can interact with other medications, including MAOIs, antihypertensives, and other stimulants. Inform your doctor about all the medications and supplements you are taking to avoid potential interactions. FDA Access Data
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