Tramadol 200mg Extended-Release (ER) tablets are a prescription medication used to manage moderate to moderately severe chronic pain in adults who require continuous, around-the-clock treatment. This formulation provides sustained pain relief over a 24-hour period, reducing the need for frequent dosing. Tramadol is a centrally acting analgesic with dual mechanisms: it binds to μ-opioid receptors and inhibits the reuptake of norepinephrine and serotonin, contributing to its pain-relieving effects .AdvaCare Pharma+1Minimally Invasive Neurosurgery Clinic+1Minimally Invasive Neurosurgery Clinic+1Wikipedia+1
Dosage and Administration
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Strength: 200mg per tablet
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Form: Extended-release oral tablet
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Typical Use: Once daily, swallowed whole with or without food. Do not crush, chew, or split the tablet, as this can lead to rapid release and absorption of a potentially fatal dose .Wikipedia+4RxList+4Lupin+4MedLibrary.org
Indications
Tramadol 200mg ER is indicated for the management of chronic pain that requires continuous, long-term opioid treatment when alternative options are inadequate .Minimally Invasive Neurosurgery Clinic+1MedLibrary.org+1
Warnings and Precautions
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Addiction and Misuse: Tramadol has a risk of addiction, abuse, and misuse, which can lead to overdose and death. It is subject to a Risk Evaluation and Mitigation Strategy (REMS) by the FDA .
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Respiratory Depression: Serious, life-threatening, or fatal respiratory depression may occur, especially during initiation or dose increases .
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Seizure Risk: Tramadol may increase the risk of seizures, particularly in patients taking certain medications or with a history of seizures .
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Serotonin Syndrome: Risk increases when combined with serotonergic drugs .
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Contraindications: Not recommended for children under 12 years, or under 18 years following tonsillectomy or adenoidectomy .Medical News Today+1MedLibrary.org+1Lupin+1Medical News Today+1MedLibrary.orgWikipedia
Common Side Effects
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Nausea
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Dizziness
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Constipation
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Headache
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Drowsiness
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Dry mouthMedical News Today+8Health Warehouse+8AdvaCare Pharma+8MedLibrary.org+4AdvaCare Pharma+4Health Warehouse+4
Serious Side Effects
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Respiratory depression
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Seizures
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Serotonin syndrome
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Severe allergic reactions
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Adrenal insufficiency
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Androgen deficiencyMinimally Invasive Neurosurgery Clinic+6Medical News Today+6WebMD+6
Storage
Store at 25°C (77°F); excursions permitted to 15–30°C (59–86°F). Keep out of reach of children to prevent accidental ingestion, which can be fatal .RxListMedLibrary.org
Important Note
Tramadol 200mg ER should only be used under the supervision of a qualified healthcare provider. It is not suitable for as-needed pain relief or for patients with certain medical conditions, such as severe asthma, respiratory depression, or gastrointestinal obstruction .
For more detailed information, consult your healthcare provider or refer to the FDA-approved prescribing information.
FAQs for Tramadol 200mg
1. What is Tramadol 200mg ER used for?
Tramadol 200mg ER is prescribed to manage severe and persistent pain that requires continuous, long-term opioid treatment when other pain relievers are inadequate. DailyMed
2. How should I take Tramadol 200mg ER?
Take one tablet once daily, at the same time each day. Swallow it whole with water; do not crush, chew, or split the tablet, as this can lead to rapid release and absorption of a potentially fatal dose. sjhc.london.on.ca+1Drugs.com+1
3. How long does it take to feel pain relief?
While immediate-release tramadol provides relief within 30 to 60 minutes, the extended-release form may take a day or two to reach full effect. Drugs.com+2nhs.uk+2sjhc.london.on.ca+2
4. What are the common side effects?
Common side effects include nausea, dizziness, constipation, headache, drowsiness, and dry mouth.
5. Can I become addicted to Tramadol?
Yes, tramadol carries a risk of addiction, abuse, and misuse, which can lead to overdose and death. It’s important to take it exactly as prescribed and discuss any concerns with your healthcare provider. MedlinePlus+2nhs.uk+2nhs.uk+2
6. What should I do if I miss a dose?
If you miss a dose, take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at once. nhs.uk
7. Can I stop taking Tramadol suddenly?
No, stopping tramadol abruptly can lead to withdrawal symptoms. Consult your doctor for a plan to gradually reduce the dosage. nhs.uk+1nhs.uk+1
8. Who should not take Tramadol 200mg ER?
Tramadol ER is not recommended for:
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Children under 12 years old.
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Children under 18 years old after tonsil or adenoid surgery.
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Individuals with severe asthma or breathing problems.
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Those with a history of seizures or head injuries. Mayo Clinic
9. Can I take Tramadol with other medications?
Tramadol can interact with other drugs, especially those that affect serotonin levels, such as antidepressants. Inform your doctor about all medications and supplements you’re taking. HealthlineMayo Clinic+1WebMD+1
10. Is Tramadol safe during pregnancy or breastfeeding?
Tramadol use during pregnancy can lead to withdrawal symptoms in the newborn. It’s also not recommended during breastfeeding, as it can pass into breast milk and harm the baby. Drugs.com
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